VCU researchers receive $2.1 million grant to investigate genetic markers for schizophrenia

The National Institute of Mental Health has awarded a $2.1 million grant to Virginia Commonwealth University’s Center for Biomarker Research and Precision Medicine to study potential epigenetic causes of schizophrenia.

The purpose of the four-year grant is to study DNA methylation as it relates to the development of schizophrenia. Methylation is a process that involves small changes to DNA that can be inherited or be the result of environmental factors such as smoking, dietary habits and medical treatment.

“DNA methylation changes over time,” said principal investigator Karolina Aberg, Ph.D., associate director of the Center for Biomarker Research and Precision Medicine and assistant professor at VCU School of Pharmacy. “Age is one aspect that changes methylation patterns, but habits like what you eat and drink and how much you exercise can also have an effect.”

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