Virginia Commonwealth University has received a $378,026 grant from the Global Alliance to Prevent Prematurity and Stillbirth to look for predictors of preterm birth and other adverse pregnancy outcomes in pregnant women.
The two-year Human-Microbiome Alterations Predictive of Prematurity (HAPP) study will expand on two earlier studies under the National Institutes of Health’s Human Microbiome Project that looked at microbial communities in pregnant women and how changes in communities of bacteria, viruses and human cells affect women’s health.
“We’re looking at the microbiome as women go through pregnancy to try to determine what the roles of the microbiome are and its impact on the reproductive tract,” said Gregory Buck, Ph.D., professor of microbiology and immunology at the VCU School of Medicine and director of the VCU Center for the Study of Biological Complexity.
Buck is leading the study with Jennifer Fettweis, Ph.D. (Ph.D.’09/M), assistant professor in the Department of Obstetrics and Gynecology at the VCU School of Medicine and the VCU Center for the Study of Biological Complexity. The team has been applying omics technologies to investigate both the human host cells and the microbiome.